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From The Collaborative International Dictionary of English v.0.44 [gcide]:
Irrespective \Ir're*spec"tive\ ([i^]r'r[-e]*sp[e^]k"t[i^]v), adjective
1. Without regard for conditions, circumstances, or consequences; unbiased; independent; impartial; as, an irrespective judgment.
According to this doctrine, it must be resolved wholly into the absolute, irrespective will of God. --Rogers.
2. Disrespectful. [Obs.] --Sir C. Cornwallis.
{Irrespective of}, regardless of; without regard to; as, irrespective of differences.
From WordNet (r) 2.0 [wn]:
irrespective
adverb: in spite of everything; without regard to drawbacks; "he carried on regardless of the difficulties" [syn: {regardless}, {disregardless}, {no matter}, {disregarding}]
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