From The Collaborative International Dictionary of English v.0.44 [gcide]:
1. The act of aggravating, or making worse; -- used of evils, natural or moral; the act of increasing in severity or heinousness; something additional to a crime or wrong and enhancing its guilt or injurious consequences.
From WordNet (r) 2.0 [wn]:
From Moby Thesaurus II by Grady Ward, 1.0 [moby-thes]:
122 Moby Thesaurus words for "aggravation": accelerando, acceleration, adverse circumstances, adversity, affliction, agitation, animation, annoyance, annoyingness, arousal, arousing, bad news, bedevilment, beefing-up, blight, blowing up, blowup, bore, bother, botheration, bothersomeness, bummer, care, concentration, condensation, consolidation, crashing bore, cross, curse, deepening, devilment, difficulties, difficulty, disapprobation, disapproval, discontent, displeasure, dissatisfaction, dogging, downer, drag, electrification, enhancement, exacerbation, exaggeration, exasperation, excitation, excitement, exhilaration, explosion, fomentation, galvanization, harassment, hard knocks, hard life, hard lot, hardcase, hardship, harrying, headache, heating-up, heightening, hounding, incitement, inflammation, information explosion, infuriation, intensification, irksomeness, irritation, lathering up, magnification, molestation, nuisance, persecution, perturbation, peskiness, pest, pestiferousness, pickup, plaguesomeness, plight, population explosion, pother, predicament, pressure, problem, provocation, provokingness, redoubling, reinforcement, resentfulness, resentment, rigor, sea of troubles, speedup, steaming up, step-up, stimulation, stimulus, stirring, stirring up, strengthening, stress, stress of life, tightening, tiresomeness, trial, tribulation, trouble, troubles, troublesomeness, vale of tears, vexation, vexatiousness, vicissitude, wearisomeness, whipping up, working up, worriment, worrisomeness, worry
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