From The Collaborative International Dictionary of English v.0.44 [gcide]:
2. Something difficult; a thing hard to do or to understand; that which occasions labor or perplexity, and requires skill and perseverance to overcome, solve, or achieve; a hard enterprise; an obstacle; an impediment; as, the difficulties of a science; difficulties in theology.
From WordNet (r) 2.0 [wn]:
From Moby Thesaurus II by Grady Ward, 1.0 [moby-thes]:
168 Moby Thesaurus words for "difficulty": Gordian knot, abstruseness, adverse circumstances, adversity, affliction, aggravation, agreement to disagree, altercation, annoyance, arduousness, asperity, bad news, bedevilment, beef, bickering, blight, block, blockade, bore, bother, botheration, bothersomeness, bottleneck, bummer, burden, burthen, care, cargo, catch, challenge, charge, complexity, complication, controversy, cordon, crabbedness, crampedness, crashing bore, cross, cross-purposes, cumbrance, curse, curtain, deadweight, deepness, demurral, demurrer, determent, deterrent, devilment, difference, difference of opinion, difficulties, dilemma, disadvantage, disagreement, disparity, dispute, distress, dividedness, division, dogging, downer, drag, drawback, embarrassment, emergency, encumbrance, esoterica, exasperation, exigency, falling-out, fight, fix, formidableness, freight, hamper, handicap, hang-up, harassment, hard knocks, hard life, hard lot, hardcase, hardness, hardship, harrying, hassle, hazard, headache, heavy sledding, hindrance, hitch, hot water, hounding, hurdle, impediment, impedimenta, imposition, inconvenience, intricacy, irritation, jam, joker, knottiness, laboriousness, load, lumber, mess, misunderstanding, molestation, nuisance, objection, obstacle, obstruction, obstructive, odds, one small difficulty, onus, pack, painfulness, pass, penalty, persecution, pest, pickle, pinch, pitfall, plight, polarization, predicament, pressure, problem, profoundness, profundity, protest, quandary, question, reconditeness, remonstrance, remonstration, rigor, rub, scrape, sea of troubles, snag, squabble, strain, strait, straits, stress, stress of life, stumbling block, stumbling stone, trial, tribulation, trouble, troubles, vale of tears, variance, vexation, vexatiousness, vicissitude, vigor, weight, white elephant, worriment, worry
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